Natural Health News – A new analysis has concluded that while that vitamin D deficiency may increase the risk of several serious health disorders, supplementation may not reduce the risk.
Although the headlines might suggest this latest study is the last word on the subject, in fact, the meta-analysis raises more questions than answers.
vitamin D deficiencies and the use of supplements have been debated for years. Several recent studies suggest that a number of factors, including increasingly styles of interior life means that we are becoming vitamin D deficient. Deficiency of vitamin D is associated with a variety of health problems Chonic, but at the same time there is no doubt that vitamin D plays a role in bone health, but their role in non-skeletal disorders remains unclear .
Researchers at the International Institute for Prevention Research in Lyon, France reviewed 290 prospective studies and 172 randomized trials, to help them understand more about the role of vitamin D s in the disease and the possible benefits of supplements. Their results have been published in the journal Lancet Diabetes and Endocrinology .
All studies included in the analysis used blood levels of vitamin D to determine whether participants were vitamin D sufficient or deficient before measuring health outcomes.
Benefits for heart disease and diabetes
The trials used both cholecalciferol (vitamin D3) and ergocalciferol supplementation (vitamin D2). All trial participants had baseline vitamin D levels below 50 nmol / L (which is considered a minimum healthy level).
In observational studies, vitamin D deficiency was associated with an increased risk of cardiovascular disease, inflammation, impaired glucose metabolism, infectious diseases, mood disorder, reduced cognitive function, and even mortality from all causes.
adequacy of vitamin D was associated with a lower risk of cardiovascular events (in 58% of observational studies), diabetes (38%), colorectal cancer (33%), and mortality all cause (29%).
colorectal, however, was the only cancer risk appeared to be reduced by having enough vitamin D in the blood.
However, they found that none of the randomized clinical trials reviewed confirmed this finding.
According to the lead author Philippe Autier, MD, MPH, and colleagues, concentrations low blood vitamin D were associated with a variety of acute and chronic disorders through implicated inflammatory process with the disease . This led the researchers to conclude that low levels of vitamin D come naturally with age and are a consequence of poor health, not a cause.
But it was enough dose?
Note that this meta-analysis included studies of different types of vitamin D in a range of doses. This may explain the lack of consistency in the results. In addition, older trials may have used much smaller than those that we now know are necessary to help patients achieve vitamin D sufficiency of
For example, the only larger trial reviewed by the authors, the Health Initiative of Women, only supplemented with 400 IU per day -. this may have skewed the overall results
these days it is recommended that we need a daily maintenance dose of 600iu. For treating vitamin D deficiency, the daily dose is between 2,000-3,000iu per day. Newer tests using doses at this level.
Furthermore, very little attention to what could help the absorption of the additional vitamin D. For example, a recent study found that intestinal health plays an important role in vitamin D sufficiency and take a probiotic supplement with vitamin D supplementation could, improves vitamin D status .
However, in a small number (34) of vitamin D clinical trials disabled people did not improve after taking 50 mcg (2000IU) of vitamin D per day. However, in a subgroup of patients older group, mostly women, supplementation with 20 mcg (800IU) yes slightly reduced mortality from all causes.
The researchers suggest that more trials of supplementation of vitamin D. These results may help to clarify these things are needed, say they are taking place now.