ultrasound significantly improves the ability of vitamin C and niacinamide reducing hyperpigmentation, according to research Japan.
Researchers noted with frustration that hyperpigmentation and dark spots were difficult to deal with skin lightening agents. This is due to limitations in delivering them through the epidermis. So they decided to find out what would happen if ultrasound is used with a gel containing ascorbyl glucoside (vitamin C) and niacinamide.
The trial in 60 Japanese women with hyperpigmentation over four weeks and the results were evaluated by computer analysis and self-perception. The conclusion was that ultrasound along with vitamin C and niacinamide gel skin lightening “significantly reduces facial blemishes hyperpigmented compared with both no treatment and skin lightening gel.”
Good to know! But scientists do not end there because, of course, want to know why ultrasound helps the penetration of these vitamins and other active ingredients for topical application. In a book on the issue of absorption of topical skin treatments, the authors (Robert Bronaugh and Howard Mabach) speculate that the ability of ultrasound to improve absorption may be due to the way it interacts with lipids ultrasound structured in the stratum corneum.
In a useful summary of several studies suggest that ultrasound was shown to increase the rate of diffusion of oxygen through the skin (frogs). Other researchers suggest that (subsensory) ultrasonic vibrations create microscopic bubbles on the surface of the skin and somehow this increases skin permeability.
Although the mechanism by which the ultrasound improves product penetration seems to have not yet defined, Bronaugh and Mabach are in no doubt that the effects are palpable and speculate that some ultrasound day is used instead of needles to deliver drugs such as insulin.