letters in recent weeks, I’ve received from people terrified that their serum vitamin C are going to get cancer. In some cases, a specific form of vitamin C called ascorbyl palmitate was identified for concern, while other writers were about to destroy anything in your medicine cabinet. Graciously, everyone has sent me some links that I was able to see its sources. From their concerns were shocking and research seemed worrying, I began to try to find out the truth about vitamin C and ascorbyl palmitate.
A 2002 study by the ascorbic acid-6-palmitate
Synonyms for this ingredient are ascorbate-6 palmitate, ascorbyl palmitate and vitamin C palmitate.
The Meves found was that 6-palmitate scorbic acid strongly promotes lipid peroxidation induced-By ultraviolet concluded that “despite its antioxidant properties, ascorbic acid-6-palmitate acid may enhance skin damage after physiological ultraviolet radiation “and noted that this was” probably “due to its” lipid component doses. ”
This sounds definitive, but is it?
Calls for more research
Not long after the Meves 2002 study, article in the Journal of Investigative Dermatology, spoke in this regard, noting “it is clear from the study reported by Meves et al that ascorbyl-6-palmitate is no ascorbic acid.” then the author went to question whether ascorbyl-6-palmitate could penetrate the stateum layer or interefere with its own built in the form of antioxidant defense, which alters the lipid barrier or even penetrate deeper and damage cell layers of the skin. The conclusion was “only additional in vivo studies that allow us to assess the potential damage to the skin.”
Thus there has been more research?
The study Meves 2002 on the harmful effects of ascorbic acid-6-palmitate appears to be unique in its kind. I can not find other studies that attempt to reproduce the results to support or refute them. I went through toxicology reports on PubMed and Meves study done are listed there. But it is the only one that refers to the harmful effects.
Research on ascorbyl palmitate is mostly positive. In fact, the history of research is very positive. For example, a 2006 study in mice showed that ascorbyl palmitate administered topically twice a week inhibited 91% of tumors.
One study from 2014 found that this ingredient prevented cell death X-ray. I will also mention research from 2013 on how ascrobyl-6-palmitate lipid peroxidation inhibited – concluded exactly the opposite of what got us into this started (although I found it a bit strange that study humans and soybeans). In 2011, researchers found that “vitamin C palmitate (VCP), a soluble form in lipids, is integrated into the human erythrocyte membranes and prevents oxidative damage”
other scientific (in 2013) have you been happily looking for ways to improve get ascorbyl palmitate on the skin, apparently unconcerned by the study 2002.
in a negative study of China reached found that ascorbyl palmitate had a low antioxidant activity, ascorbic acid was high.
could go on and on. As I said, the family tree research for the safety of ascorbyl palmitate seems sound.
So why the sudden surge of concern about cancer?
The short answer is I’m not sure. However, a 2014 article Felicia Rose laboratories has been passed around.
The writer says that the molecules of palmitate “lover convert skin of vitamin C in a dangerous substance tested.” This process of stabilization of vitamins leads to “Skin cancer and accelerated aging of the skin.” This is entirely based on the Meves study from 2002.
She concludes that it must be alert to any linked vitamin palmitate, including vitamin A. This is based on the findings of the National Board of Toxicology that retinyl palmitate is carcinogenic when exposed to sunlight. What happens is that the NTB also said that retinoic acid, retinyl palmitate increased not only skin lesions and photocarcinogenic activity.
Facing one, raising concerns study unreplicated and many more that are the effects on the skin to be beneficial, I see no reason to stop using products with the ingredient ascorbyl palmitate.