Scientists probe the anti-cancer properties of wild North American berry

Natural Health News – New research has shown that chokeberry – which grows abundantly in North America – has anti-cancer properties and may even improve the effectiveness of conventional cancer treatments

UK scientists based their findings on a laboratory study on the effectiveness of the extract. black chokeberry (melanocarpa Aronia ) to kill cancer cells. – A process known as apoptosis

Aronia is a wild berry that grows on the eastern side of North America in wetlands and marshes, as well as parts of Europe. Berry is rich in vitamins and antioxidants, including various polyphenols – compounds believed to mop the harmful byproducts of normal cell activity. In food supplements and drinks often sold as Aronia.

For this study, researchers tested an extract of Aronia in pancreatic cancer cells. They examined what happened to these cells in the laboratory when treated with chemotherapy alone, chokeberry extract alone, or a combination of both.

What they found was that the addition of chokeberry extract to gemcitabine (a chemotherapy drug used in the treatment of pancreatic cancer) was more effective in stopping the growth of cancer cells than the drug alone.

The researchers chose to study the impact of the extract on pancreatic cancer because of its persistently dismal prognosis. Less than 5% of patients are alive five years after diagnosis

Analysis of Journal of Clinical Pathology first considered the general toxicity of chokeberry. It was found that chokeberry had no toxic effect on normal cells lining, even at the highest doses. This suggests, the researchers, who may not be able to prevent the formation of new blood vessels (antiangiogenic properties), a process that is important in the growth of cancer cells say.

An additive effect

However, the scientists also found that after 48 hours of treatment with the extract of wild berries was no evidence of apoptosis in cells pancreatic cancer.

In addition, low doses of the extract greatly increased the effectiveness of gemcitabine, when the two were combined, added to which conventional lower drug doses are needed.

This suggests that the compounds work together synergistically, or that the extract has a “supra-additive” effect, researchers say.

They will say that the potential of naturally occurring micronutrients in plants, such as those found in chokeberry, has not been adequately, at least explored in clinical trials.

Research in its early stages, but scientists say similar experimental studies, indicating that the extract of chokeberry appears to induce cell death and stop the invasion of brain cancer as well as other research, highlighting the potential therapeutic effects of certain polyphenols similar to those found in green tea, soy, grapes, mulberries, peanuts and turmeric.

“This work adds first reinforcement for the concept that cancer therapy difficult solution could be useful augmented by the inclusion of micronutrient supplementation regimes,” the researchers write.

“More specifically, it is suggested that elements in chokeberry extract, although not inherently toxic, can have additive effects above-combination with at least one other conventional cytotoxic drug” conclude.

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