Macular degeneration linked to immune abnormalities in retina

by: Lunardo Emily | eye ​​health | Friday, August 19, 2016 – 14:30


mauclar degeneration linked to immune abnormalities in retina macular degeneration was found to be related to immune abnormalities beneath the retina. The new findings could help prevent vision loss associated with this eye condition. The researchers focused on two protective mechanisms involved in the gradual onset of macular degeneration, which degrades and destroys central vision.

The retinal pigment epithelium is a layer of cells at the back of the eye that performs a number of functions that are crucial for vision health. This is where macular degeneration begins, as immune proteins that are supposed to kill disease-causing organisms, stop doing your job properly.

Investigator Aparna Lakkaraju said: “These studies raise the possibility of treatments that may delay or prevent macular degeneration cells that detect light in the retina are totally dependent on the RPE [retinal pigment epithelium] for survival. but the RPE cells are not replaced throughout life. “

researchers hope to develop a drug to specifically target these alterations in immune proteins and thus restore the protection mechanisms in the retinal pigment epithelium of the retina, preventing vision loss caused by macular degeneration.

Tests in mice have demonstrated the success of macular degeneration drugs available in the market in preventing damage to cells in the eye.

How macular degeneration affects vision?

macular degeneration (AMD) is a disease that progresses with age. It begins to affect people over 40 by hindering the sharp, central vision. The central vision used for activities such as reading or driving. With the deterioration of central vision, making everyday tasks becomes very difficult.

AMD affects the macula, the central part of the retina allows us to see fine details. AMD can take two forms :. Wet and dry

The causes of macular degeneration related to age depend on its type. In wet AMD, abnormal behind the retina blood vessels grow under the macula, leading to blood and fluid leakage. This form of AMD is often characterized by a rapid loss of central vision.

In dry AMD, moreover, the macula becomes thinner with age. Approximately 70 to 90 percent of AMD cases are in the dry form. Unlike wet AMD, dry AMD progresses slowly, which affects one eye or both eyes.

The greatest risk factor for macular degeneration is age-related aging . People may begin to notice changes in your central vision and at the age of 40. Other uncontrollable risk factors for AMD include race – Caucasians are more likely to develop AMD -. and family history

The use of corrective lenses, either glasses or contact lenses may help improve central vision. annual checkups with an ophthalmologist are important to monitor the progress of AMD. Regular visits to optometrists are the key to early detection of the onset of AMD.

Like an unhealthy diet can increase the risk of developing macular degeneration related to age, a healthy diet can improve the condition. Make sure you are enjoying a variety of fruits and vegetables, which are nutrient power.

eye ​​exercises can help maintain vision. healthy lifestyle habits can also help support eye health. Not smoking, controlling blood pressure and cholesterol, and use protective glasses – sunglasses, safety glasses -., Can contribute to healthy vision and slow the progression of macular degeneration related to age

Sources:
http://news.wisc.edu/macular-degeneration-insight-identifies-promising-drugs-to-prevent-vision-loss/
http://www.belmarrahealth.com/age-related-macular-degeneration/


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