Sometimes medications people have taken a long time to be authorized to become less suitable, possibly even dangerous , as patients get older. popular drugs used to treat heartburn, probably should be considered in this category, although they are not usually listed as drugs that are too risky for the elderly.
Does Nexium Weakening bones?
P My wife and I are in our 70s She has been taking Nexium for years. Recently read that this type of medicine may increase your risk of bone fracture. How can this be true?
A. inhibitors such as esomeprazole acid drugs (Nexium), lansoprazole ( Prevacid ) and omeprazole ( Prilosec ) interfere with the absorption minerals such as calcium and magnesium. A recent in article Journal of the American Geriatrics Society (November 2015) suggests that the adoption of such proton-pump inhibitor (PPI) for more than two months could be too risky for the elderly. Can lead to intestinal infection C. diff infections as well as bone loss and fractures. The most recent meta-analysis confirms that regular use of PPIs may increase the risk of both fractures of the hip and spine ( International Journal of Clinical and Experimental Medicine June 2015 ).
Older people are not the only ones at risk:
There is a lot of evidence that all those who take a PPI for more than two months may experience some undesirable side effects. One that has been hotly debated by gastroenterologists is probability rebound reflux ( Gastroenterology July 2009 ). Volunteers with no history of reflux symptoms of heartburn or indigestion suffered for several weeks when they stopped taking Nexium suddenly after being on it for two months.
Changes in intestinal bacteria:
There was an increased scientific attention to the importance of the balance of bacteria living in our digestive tract. A recent experiment indicates that changes in the ecology of the microbiome can faciliate infection Clostridium difficile , a type of bacteria that can cause unpleasant diarrhea and difficult to treat ( Gastroenterology October 2015 ).
We send our Guide Digestive Disorders with a discussion of the pros and cons of these medications and alternatives. It also has information about tactics to get out of a PPI.