What is forskolin?
Forskolin is a chemical that is extracted from the roots of the Indian Coleus plant ( Coleus forskohlii ). The plant itself is a tropical perennial herb of the mint family (Lamiaceae) and originates from India and East Africa. It is an ornamental plant with colorful leaves. Forskolin is a chemical compound type labdane diterpene, which is known to have antibacterial, antifungal, anti-inflammatory, antispasmodic and antiprotozoal activities.
What are the health benefits of forskolin?
Coleus forskohlii plant has been used for centuries to treat respiratory disorders such as asthma, chest pain associated with heart problems and high blood pressure. Forskolin seems to help activate an enzyme called adenylate cyclase which increases the amount of cyclic adenosine monophosphate (cAMP) in living cells. Cyclic AMP is an essential compound of cellular regulation and is involved in a variety of cellular activities. In recent years, the medicinal uses of forskolin have increased and is now being used to treat allergies, urinary tract infections (UTI), bladder infections, skin diseases such as psoriasis, eczema and rashes, obesity, menstrual cramps, blood clots, erectile dysfunction in men, sleep disorders and irritable bowel syndrome (IBS) 1 .
What are the uses of forskolin
Forskolin is a folk remedy for weight loss and acting as an effective fat burner by promoting the decomposition of stored fat in fat cells. Its function is to stimulate lipolysis and increasing the levels of cyclic AMP. The synthesis of cyclic AMP in fat cells triggers a series of events that leads to the hydrolysis of stored triglycerides, which subsequently free fatty acids and glycerol is released from fat cells 2 .
Researchers at the Faculty of Medicine at Penn State University found that cyclic AMP levels were lower in many obese people. This suggests that forskolin may be effective in weight loss, especially for people suffering from impaired production of cyclic AMP. A recent study concluded that forskolin can be a useful and safe supplement for weight loss and maintenance of normal body composition 3 .
Forskolin has also become a popular supplement for body builders and athletes because it helps to release fatty acids from adipose tissue. This results in a loss of body fat and increase in lean body mass. In addition, unlike many other stimulants the central nervous system forskolin not seem to have undesirable side effects such as nervousness, anxiety, insomnia, tachycardia, elevated blood pressure, or seizures.
A weight loss remedy is recommended to take capsules of 250 mg twice daily for 12 weeks forskolin.
A decrease in cyclic AMP in bronchial smooth muscle contractions can cause the bronchial tubes, which can trigger asthma symptoms. Since forskolin helps increase the production of cyclic AMP, a recent study suggests forskolin may be more effective in suppressing the symptoms of asthma than other nutraceuticals 6 . The study suggests that making Forskolin 10 mg once a day for 2 to 6 months may help patients suffering from asthma by increasing cAMP production.
high blood pressure and congestive heart failure
Congestive heart failure (CHF) is a condition that affects the pumping power of the heart muscles. Reportedly, forskolin helps strengthen the heart muscle and blood vessels widents helps produce a stronger heartbeat. It also helps lower blood pressure levels by reducing the resistance to blood flow. Therefore, taking a capsule containing extract 10% forskolin forskolin expected, it could help treat both the ICC and high blood pressure.
Eye problems and glaucoma
Forskolin drops are used in the treatment of ocular hypertension, and the IOP (intraocular pressure) or glaucoma. One study suggests that the use of forskolin 2 drops of 1% eye drops 3 times a day can be a safe alternative to beta blockers in glaucoma patients with concomitant asthma 4 .
Psoriasis is caused by uncontrolled cell proliferation and division, and increased levels of a cell regulator cGMP (cyclic guanosine monophosphate) which cancels and dominates cyclic AMP. Forskolin can normalize cGMP and cAMP balance, proliferation thus standardization and cell division. Therefore take 1 capsule daily forskolin can help treat the symptoms of psoriasis.
Erectile dysfunction (ED)
Preliminary research indicates that forskolin can improve sexual function in men suffering from erectile dysfunction. Therefore, take one capsule of 250 mg of forskolin a day can be beneficial 7 .
An experimental study suggests that forskolin can help increase the production of thyroid hormones and stimulate their release when needed. Because of their ability to normalize thyroid function, forskolin can facilitate weight loss by enhancing their metabolic rate. A 250 mg capsule daily supplement forskolin may be beneficial to treat hypothyroidism.
people with symptoms of depression have reduced levels of cyclic AMP are known. Since forskolin increases the levels of cyclic AMP, there is no evidence that it can help raise mood levels 5 . One suggested solution for depression is therefore make a 250 mg capsule daily forskolin.
What are the side effects of forskolin?
Forskolin is not toxic and is considered safe when used in moderation. If any unusual side effect is observed, discontinue use of forskolin and consult your doctor. Like any other natural or herbal product, caution should also be careful when taken in combination with other medicines herbal or allopathic.
Pregnant and lactating women should avoid using forskolin and there is not enough reliable information regarding the safety of taking it during pregnancy or breastfeeding. Forskolin is not recommended if you have polycystic kidney disease.
Since forskolin can lower blood pressure, should monitor their blood pressure levels during use. Also, if you are taking epinephrine or any medication to treat high or low blood pressure, forskolin should be avoided as it may interfere with medication.
Forskolin should be discontinued at least 2 weeks before any surgery to avoid bleeding risk as it promotes blood flow. You should also be avoided if you are taking any anticoagulant medication.
How and where to buy forskolin?
Forskolin can be purchased at most grocery stores herbal or online. When buying forskolin find a product that is standardized to 10% -20% of forskolin in 250 mg capsules / tablets.