Gonorrhea may become resistant to all antibiotics sooner than anticipated

experts have been concerned for a moment that time is running out for the last priests working for gonorrhea infections. On Wednesday, they revealed that some may have even less time on the clock than previously thought.

Scientists at the Centers for Disease Control and the Department of Health Prevention and Hawaii reported a cluster of cases of gonorrhea in the state in which the bacteria Neisseria gonorrhoeae showed high level of resistance to a drug, azithromycin and reduced susceptibility to second drug, ceftriaxone.

The two drugs are used in combination, a move that experts expect inexorable march of the bacteria will slow through antibiotic medicine cabinet.

The article continues after the announcement

had has already been signs bacteria, which have won several other antibiotics, were beginning to be able to evade these ones too. Since 2005, there have been four isolated cases reported in which the bacteria Neisseria gonorrhoeae had reduced susceptibility to both drugs. But this is the first time a group of these cases has been seen in the US ..

“Our last line of defense against gonorrhea is weakening,” Dr. Jonathan Mermin, director of the National Center for HIV / AIDS, Viral Hepatitis, STD, and TB CDC said in a statement.

“If the resistance continues to grow and spread, the current treatment fail and 800,000 Americans per year are at risk of untreatable gonorrhea.”

Untreated gonorrhea can cause chronic pelvic pain, infertility and ectopic pregnancy – in which a fertilized egg begins to develop in a fallopian tube, uterus no. Ectopic pregnancies can be life threatening.

The case group described by Dr. Alan Katz, the state board of health Hawaii involved six men and a woman, but was in fact undoubtedly larger. They do not have sex with each other, so they must have been infected by other people.
Katz said seven people reported a total of eight sexual partners. Four of the eight agreed to be tested, but none were infected.

Analysis of the genetic sequences of the virus showed that they were closely related, Katz said.

Seven people were cured of their infections. But it seems only a matter of time before treatment failures occur. Earlier this year, doctors in Britain reported that a man infected with gonorrhea not cured by their first course of antibiotics, but treatment follow-up three months after infection quelled.

If this combination of drugs fail, there is no other treatment option available today. Several experimental antibiotics are in development and one has recently been shown to be effective in a Phase 2. But still probably years away from hitting the market.

hyacinth Steeply / STAT
The superbugs are growing in number and strength and it is our fault.

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