Natural Health News – allicin extracted from garlic can help fight resistant bacteria antibiotics that cause lung infections in people with cystic fibrosis, according to researchers at the University of Edinburgh.
Burkholderia cepacia complex (CCO) is said to be a major cause of life-threatening lung infections in patients with cystic fibrosis, treatment that currently require the combination of three or four different antibiotics .
The researchers said the study, published in the journal PlosOne , went to his knowledge the first evidence of allicin and the ability of the extracts garlic ‘to inhibit and kill CCO contains allicin. Allicin is a present thiosulphinate in crushed garlic bulbs.
The data point in particular to pure allicin and, more importantly, allicin in garlic aqueous extracts.
Professor John Govan, who co-led the study, said: “ At a time when urgent new antimicrobial agents are needed, chemical and microbiological research has the potential to unlock the rich reserve antimicrobial compounds present in plants such as garlic.
“compounds containing allicin warrant further investigation as adjuncts to treatment for infections caused by existing CCO.”
according to researchers therapeutic potential and the complex chemistry of alliums like garlic ( Allium sativum L ) was well documented but remained “enigmatic.”
Further research on the mechanisms underlying this effect, however, noted that previous research suggesting allicin reacts with the amino acid cysteine to stop antimicrobial activity.
In response to the findings, research manager senior in Cystic Fibrosis Trust, Dr. Anoushka de Almeida, he said the Trust welcomed the progress made these results in the fight against antibiotic resistance .
“antibacterial resistance is one of the biggest challenges facing modern medicine and people with cystic fibrosis are particularly susceptible to infections that require weeks of antibiotics, and measures must be taken by the scientific and medical community to address the issue of increasingly ineffective treatments.
“Although research on how the compounds of garlic can be effective in killing certain bacteria is still at an early stage, this study opens the door to further research into allicin and its antimicrobial properties. “
this study confirms previous evidence that gives an idea of garlic extracts have can work .
the bacteria may be present in two different forms, either as single cells or as a group of bacteria together by a sticky film (known as biofilm). Biofilm infections, such as pneumonia in patients with cystic fibrosis, chronic wounds, chronic otitis media and implantable infections and catheter-associated, affecting millions of people in the developed each year world are more difficult to treat and are often chronic, even deadly.
One study 2012 researchers claimed to have identified a constituent of garlic – Ajoene – attacking a key step in the development of biofilms, which say they can offer hope, particularly for patients with cystic fibrosis. In a study in laboratory animals and significantly clear infection found Pseudomonas aeruginosa and enhance the effect of antibiotics in biofilms.