Chestnut leaf extract fights drug-resistant Staph bacteria

Natural Health News – European chestnut leaves contain ingredients that have the power to disarm the dangerous staph bacteria without promoting drug resistance.

The study of the journal PLOS ONE found that the leaf extract chestnut, was rich in two substances – ursene and oleanene – blocking Staphylococcus aureus bacteria, which causes a range of problems from minor skin irritation to death, in hospitals and in the community.

Using chestnut leaves in traditional folk remedies inspired the research, said lead researcher Cassandra Quave, an ethnobotanical at Emory University. What you need to know

The European chestnut leaves contain substances -. Ursene and oleanene

Scientists investigating the popular medicinal use of chestnut leaves found that an extract of the leaves rich in ursene and oleanene stops resistant staphylococci bacteria to antibiotics

He does not kill bacteria, but closing its ability to create toxins that cause tissue damage.

“We have identified a family of compounds of this plant has an interesting medicinal mechanism,” she said. “Instead of killing staphylococci, this botanical extract works by eliminating weapons of staphylococci, essentially shutting down the ability of bacteria to create toxins that cause tissue damage. In other words, force is needed to bite the bacteria “.

reject toxins

A single dose 50 micrograms clarified extract MRSA skin lesions in laboratory mice, stopping tissue damage and damage red blood cells. Further tests showed that this extract inhibits the ability of staph bacteria communicate with each other, a process known as quorum sensing. MRSA using this system quorum sensing signaling for the manufacture of toxins and ramp up its virulence.

The discovery has potential for new ways to treat and prevent infections methicillin-resistant S. aureus or MRSA, without feeding the growing problem of drug-resistant pathogens.

bacteria

antibiotic resistant annually cause millions of deaths each year. The evolution of strains of this bacterium “super bug” pose a threat to the two hospital patients with compromised immune systems and young, healthy athletes and others who are in close physical contact.

Restoring balance

“We have shown in the laboratory that our extract disarms even MRSA strains hyper-virulent capable of causing severe infections in healthy athletes,” says Quave. “At the same time, the extract not disturb, normal healthy bacteria in human skin. Its all about restoring balance.”

Researchers are doing more tests on individual components of the extract to determine if work best in combination or alone.

“It’s easy to dismiss traditional remedies as old wives tales, simply because they attack and kill pathogens,” says Quave. “But there are many more ways to help cure infections, and need to focus on them in the era of drug-resistant bacteria.”

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