Broccoli Helps Clear Damaged Lungs

There are a number of reasons why you should eat vegetables. At most protect our body from infection and disease. Broccoli, for example, is very useful for our body. It helps the body’s immune system clean and harmful bacteria from the lungs. The compounds consisted of broccoli help in various lung diseases.

to ensure that the lungs are functioning properly, the white blood cells called macrophages remove debris and bacteria that can accumulate in the lungs and cause infection.

Now, researchers have discovered that a chemical pathway in the lungs called Nrf2 involved in macrophage activation, is wiped out by smoking. They also found that sulforaphane, a chemical plant is by broccoli, cauliflower and other cruciferous vegetables when damaged, for example when chewed, can restore this pathway.

This cleaning system is defective in smokers and people with chronic obstructive pulmonary disease (COPD) – a combination of emphysema and bronchitis -. Who suffer from frequent infections

The Johns Hopkins University in Baltimore, Maryland, Shyam Biswal and his colleagues exposed defective macrophages from the lungs of 43 people with COPD in two species of bacteria that are common causes of COPD-related infections. In the presence of sulforaphane, Nrf2 was driven by the ability of macrophages to engulf bacteria recognize and is restored.

investigated in mice. They were exposed to cigarette smoke for a week or six months. The increased bacterial colonization of the lungs was found in them, similar to COPD. After treating mice with sulforaphane they found that bacteria were reduced. Instead of macrophage activation, sulforaphane have been shown to improve the functionality of the cells.

is sulforaphane in broccoli in its precursor form and becomes the active compound by enzymes present in saliva and intestinal bacteria, says Christopher Harvey, co-author of the investigation.

The levels of the enzyme are different inpeople, which means you can expect the doses of sulforaphane derived diet will vary between people. Other studies established beneficial effects of a diet rich in sulforaphane in immune defense she says.

Biswal says he needs three years to learn how to enhance the role of human beings lungsin. The team has begun Phase 2 clinical trials testing the compound in people with COPD. “There are many diseases that have poor lung function as a result of increased bacterial function in the lungs,” he says, “so this study can be extrapolated to these diseases as well.”


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