Natural Health News – A ginger extract may be able to stop before eruptions psoriasis they even begin.
In a recent study, funded in part by the National Psoriasis Foundation and the National Institutes of Health, found that a naturally occurring molecule known as methoxyluteolin can block a type of cells called mast cells against the effects of launch an inflammatory response.
Mast cells are the “universal cell alarm” that initiates the inflammatory cascade that leads to psoriasis, according to Dr. Theoharis Theoharides, a researcher at Tufts University co-author of the upcoming Journal of Allergy and clinical Immunology study.
They can be caused by infection, allergens, environmental factors such as pollution, or even emotional stress. Once this happens, Theoharides explained, mast cells set in motion a series of inflammatory reactions, including activation of immune cells and release of tumor necrosis factor alpha (TNF-alpha), a pro-inflammatory protein or cytokines involved in psoriatic disease.
Not only mast cells from the source of most of TNF-alpha in the body, Theoharides said, is also the only cell type that stores tailored TNF-alpha that can be released in a matter of seconds.
He and his colleagues first identified other natural molecule called luteolin, found in chamomile and artichokes, which may block mast cell . But then they discovered that methoxyluteolin, a different version of luteolin are in the Thai black ginger, was a blocker even more powerful mast.
Through a series of experiments, they found that both luteolin and methoxyluteolin inhibited the ability of mast cells to initiate inflammation, and could even block inflammation when administered before the joint cell activation mast in action, as reported in the study.
Besides being more powerful, methoxyluteolin had two other advantages, Theoharides said. It could easily be absorbed through the skin, and had no color and two attributes that are important to a topical treatment.
Although methoxyluteolin and luteolin can be found in both food sources, it is impossible to eat enough to achieve a therapeutic effect, he explained Theoharides. So he developed a topical containing purified extract methoxyluteolin.
A small group of people with psoriasis and other skin disorders have already tried the lotion, trademarked as Soft Derm, which also contains aloe vera extract, olive fruit, honey and oregano oil. So far, Theoharides said, it seems that the lotion could be a recipe for success.
Derm Gentle still has to undergo a clinical trial. However, many of the people who tested the lotion saw improvement in their psoriasis or other skin problems after one to two weeks of daily use, according to Theoharides. He hopes to obtain enough financing to launch a clinical trial soon.
About the black ginger
Ginger Black ( Kaempferia parviflora ) is a herbaceous plant belonging to the family Zingiberaceae. commonly grows in tropical Asia region. Thailand is known as Krachai Dam; In Japan it is commonly known as “black turmeric” or “black ginger”.
Traditionally, it is used as a promoter of energy and overall tonic. In the region of Southeast Asia, especially in Thailand, people drink boiled ginger sliced black tea and alcohol soaked with black ginger. Alternatively, the black ginger is a popular medicine commonly used to improve energy, and relief of gastrointestinal discomfort.
laboratory and animal studies have shown to have properties that make it a useful treatment for the treatment of allergy and related allergic diseases , and benign hyperplasia prostate as well as being a metabolic stimulant and antidiabetic . A small human trial showed potential for improve peripheral blood circulation, strengthen blood vessels and relieve symptoms of edema .