Natural Health News – New research shows that a form of vitamin B5 called pantethine significantly reduces the cholesterol.
According to the authors, the study, published in the journal Vascular Heath and risk management , confirms “the effectiveness of pantethine in a population of North America healthy who had mild to moderate cholesterol levels “and suggests that B5 is a natural for those who do not want to take alternative statin drugs.
The most common adverse effects of statins can include headaches, dizziness, muscle pain and fatigue. More serious problems include muscle and liver damage and an increased risk of developing diabetes. There is evidence that that “up to 20% of the general publication can not tolerate statins, and others have health problems that can not make them a good candidate for statin therapy,” said co-author of the current study,
John RUMBERGER, MD, a cardiologist at Princeton Longevity Center in Princeton, New Jersey.
In contrast, pantethine only rarely causes side effects, mild stomach upset is the most common. A review of studies found that supplementation led to side effects in less than 2% of people.
cholesterol For this study Rumberger and colleagues gave 120 people with a pantethine daily supplement for a period of 4 months (600 mg / day week 1 to 8 and 900 mg / day of week 9 to 16). Participants also followed a healthy diet. Those who took the supplement experienced a 11% reduction in “bad” LDL cholesterol, while the control group, which also followed a heart-healthy diet, experienced an increase of 3%.
The effect in this study is softer than with statins, but Previous studies have shown a greater effect . Many of these studies were conducted in the 1980s and 1990s, however, a renewed interest in alternative has grown as problems with statins and other cholesterol lowering drugs have emerged.
A useful next step in research would prove pantethine against statins.
pantethine In Japan it is sold as a cholesterol-lowering medication. In other parts of the world that is available as a supplement without medicinal properties. These results point the way to possible new and safer alternatives for people with cholesterol levels of mild to moderately high
What is pantethine?
a natural substance, pantethine also produced as a byproduct when the body metabolizes pantothenic acid. It is also a precursor of coenzyme A (CoA), which plays a critical role in metabolism and degradation of proteins, carbohydrates and fats.
Pantethine and pantothenic acid are found in most foods, including vegetables such as avocados and sweet potatoes, sunflower seeds and meat. Liver, oily fish, shitake mushrooms and yeasts have especially high concentrations.
as a supplement pantethine is a compound formed from pantothenic acid and cysteamine, a degradation product of the amino acid cysteine . When ingested, it is broken down into its component parts. Both substances play a crucial role in supporting a healthy metabolism of cholesterol and triglycerides and blocking the enzyme that the body uses to manufacture cholesterol.
Although pantethine is derived from pantothenic acid, substances having different functions in the body. Pantethine is biologically more active in the way that helps metabolize and mediate the production of fats.
The pantothenic acid does not have this activity, but it is critical for many other functions ranging from the production of hormones, antibodies, red blood cells, and acetylcholine, an important neurotransmitter (carries signals between cells nerve) and maintaining sugar levels in the blood.